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  Dr. Aravindhan Vivekanandhan  
     
  EDUCATION  
 
  • Post-Doctoral Training 
    Center for Biologics Evaluation and Research (CBER),
    Food and Drug Administration (US-FDA). Bethesda, MD 20892.
    Laboratory of Experimental Immunology,
    National Cancer Institute at Frederick (NCI-NIH), Frederick, MD 21702.
2005-2008
  • Ph.D
    Department of Immunology,
    Tuberculosis Research Centre (ICMR),
    Specialization: Molecular immunology and vaccine research

2000-2005
  • M.Phil
    Dept of Biochemistry and Molecular Biology
    University of Madras
    Distinction (82%)
    Specialization: Biochemistry
1999-2000
  • M.Sc
    Dept of Genetics
    Dr.A.L.M PGIBMS
    University of Madras
    Distinction (81% ) – First rank at the University level
    Specialization: Biomedical Genetics
1997-1999
  • B.Sc.
    Madras Christian College
    Distinction (80%)
    Specialization: Zoology   
1993-1996
   
  PROJECTS HANDLED
 
  1. Role of MAPK and NF-kB cross-talk in TLR induced secretion of pro-inflammatory cytokines and chemokines  in mouse myeloid dendritic cells. NCI, Frederick.
  2. Study of differential gene expression induced by unmethylated CpG in human myeloma cell line RPMI-8226 by microarray analysis. NCI, Frederick.
  3. Construction of recombinant BCG based HIV-1 epitode delivery system. Dept of Immunology, Tuberculosis Research Centre, Chennai An in vivo study on “Dual Signal Hypothesis”. Dept of Immunology, Tuberculosis Research Centre, Chennai.
 
PUBLICATIONS
  1. In-vivo study on “Dual Signal Hypothesis” & its correlation to humoral immune response using mycobacterial antigen. Aravindhan V. and Sulochana Das. Current Science, 2001 Aug; 81(3): 301-304.
  1. Th-2 immunity and CD3+CD45RBlow-activated T cells in mice immunized with recombinant bacillus Calmette-Guerin expressing HIV-1 principal neutralizing determinant epitope. Aravindhan V., Narayanan S., Gautham N., Prasad V., Kannan P., Jacobs WR Jr. and Narayanan PR. FEMS Immunol Med Microbiol. 2006 Jun; 47(1):45-55.

  2. Identification and differentiation of M. avium and M. intracellulare by PCR- RFLP analysis of the groES gene. Aravindhan V., Sulochana S., Narayanan S. Paramasivam, C.N. and Narayanan PR. Indian J Med Res. 2007 Dec;126:575-9.

  3. Contribution of MPAK and NF-kB Signaling to TLR Mediated MCP-1 Secretion. Aravindhan V. And Klinman D.M. Cytokine. 2007 July; 39 (1): 45

  4. Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines. Zhu Q, Egelston C, Vivekanandhan A, Uematsu S, Akira S, Klinman DM, Belyakov IM, Berzofsky JA. Proc Natl Acad Sci U S A. 2008 Oct 9. 105(42): 16260–16265.

  5. Mycobacterium tuberculosis groE promoter controls the expression of the bicistronic groESL1 operon and shows differential regulation under stress conditions. Aravindhan V, Christy AJ, Roy S, Ajitkumar P, Narayanan PR, Narayanan S. FEMS Microbiol Lett. 2009 Mar; 292(1):42-9.

  6. Cystatin C and Cystatin Glomerular Filtration Rate As Markers of Early Renal Disease in Asian Indian Subjects with Glucose Intolerance (CURES-32). Surendar J, Anuradha S, Ashley B, Balasubramanyam M, Aravindhan V, Rema M, Mohan V. Metab Syndr Relat Disord. 2009 May.
   
 

SCHOLARSHIP/FELLOWSHIP

 
  • Oak Ridge Institute for Science and Education (ORISE) Fellowship- visiting researcher at NIH
  • AIDS International Training & Research Programe (AITRP)- underwent 6 months training at Albert Einstein College of Medicine, yeshiva University, New York.
  • Dr.Sanjeeva raj Memorial Book Grant Scholarship was awarded at Madras Christian College for academic performance in B.Sc.
  • NET-UGC-CSIR Junior Research Fellowship (JRF) was awarded for clearing the National Level Eligibility Test Conducted by UGC-CSIR research Organizations.
  • GATE Junior Research Fellowship (JRF) was offered for clearing the National Level Graduate aptitude test for Engineering (Life Sciences).
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