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  Dr. Radha Venkatesan
   
 

Academic Qualifications  :

 

Sl No.

Institution
Place

Degree
Awarded

Year

1

Thiagaraja College, Madurai Kamaraj University, Madurai

M.Sc

1981-83

2

Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras Taramani Campus, Chennai

Ph.D

1987-92

3

Department of Genetics,
Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus, University of Madras,Chennai – 600113

Ph.D.
SRF
JRF


1991-92
1987-91

4

Council of Scientific and Industrial Research (CSIR)
Molecular characterization of Beta-globin gene mutations towards Prenatal diagnosis in Tamil Nadu

Research Associate

1992-93

  Research / Training experience :
 

S No.

Institution
Place

Position

From
(Date)

To
(date)

1

Madras Diabetes Research Foundation, Chennai

Head, Department of Molecular Genetics

Dec ‘1999

till date

2

Steno Diabetes Centre, Copenhagen on DHPLC technique and DNA sequencing technique in connection with a collaborative work on MODY

Post Doctoral Programme

1992

2000, 2001

3

Molecular Medicine, John Radcliffe Hospital, Oxford, England, UK, on the application of molecular techniques for prenatal diagnosis of Beta-Thalassaemia

Post Doctoral Programme

1992

1993

4

Council of Scientific and Industrial Research (CSIR) Molecular characterization of Beta-globin gene mutations towards Prenatal diagnosis in Tamil Nadu.

Research Associate

1992

1993

5

Taught courses on “Biochemical Genetics and Molecular Medicine” for post Graduate (M.Sc) and Pre-doctoral (M.Phil) students of Department of Genetics, University of Madras for 5 years.     

Faculty

1993

1998

6

Department of Genetics,
Dr. ALM Post Graduate Institute of Basic Medical Sciences, Taramani Campus,University of Madras,Chennai – 600 113

Ph.D.  
SRF
JRF


1991
1987


1992
1991

  #
 

Research Specialization (Major scientific fields of interest)

 

Recognized guide of University of Madras for Ph. D programme.

  Financial support received
 

S. No

          Project Title

Role

Status

Duration

Funding Agency

1

ICMR Advanced Centre for Genomics in type2 diabetes

Principal investigator
Co PI:  Dr. V. Mohan

Ongoing

2006-2011
(5 years)

ICMR

2

Search for Susceptibility genes for Type2 diabetes in Indians-Under support grant

Co-investigator            
Project Leader: Dr. V. Mohan

Ongoing

2008-2013
(5 years)

DBT

3

Genomic Analysis of MHC genes (HLA & non HLA) in type-1 diabetes in the Indian population

Co-Principal investigator
PI: Dr. NK Mehra 
Co PI: Dr. V. Mohan

Ongoing

2008-2011
(3 years)

ICMR

4

Setting   up of genetic screening service for maturity onset diabetes of young (mody) and neonatal diabetes in India

Principal investigator             
Co I: Dr. S. Kanthi Mathi       
Dr. V. Mohan

Submitted

-

ICMR

5

Screening for GCK MODY mutations (MODY-2) in South Indian population

Principal investigator 
Co I:Dr. S. Kanthi Mathi 
Ms. Ranjani Harish
Dr. V. Mohan

Submitted

-

DST

6

Replication of novel type 2 diabetes genes in early onset type 2 diabetes

Principal investigator
Co I:  Dr. V. Mohan

Submitted

-

DST

 

Recent Publications (last five years, with titles and references) also papers in press: 

 
1. Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Rao MR, Mohan V. Association of uncoupling protein 2 and 3 gene polymorphisms with type 2 diabetes in Asian Indians. J Endocrinol Invest. 2009 Sep 30. [Epub ahead of print]                      
2.
Ahluwalia TS, Khullar M, Ahuja M, Kohli HS, Bhansali A, Mohan V, Venkatesan R, Rai TS, Sud K, Singal PK (2009) Common variants of inflammatory cytokine genes are associated with risk of nephropathy in type 2 diabetes among Asian Indians. PLoS ONE 4(4):e5168. Epub 2009 Apr 9.
3.
Radha V, Ek J, Anuradha S,Hansen T,Pedersen O, Mohan V (2009) Identification of novel variants in the hepatocyte nuclear factor 1 alpha gene  in South Indian patients with maturity onset diabetes of young, J Clin Endocrine & Metabolism, March 31, doi:10.1210/jc.2008-2371.
4.
Vimaleswaran KS, Radha V, Ramya K, Babu HN, Savitha N, Roopa V, Monalisa D, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians. Human  Genetics. 2008 May 9. [Epub ahead of print]
5.
Bodhini D, Radha V, Monalisa Dhar, Narayani N, Mohan V. The rs12255372 (G/T) and rs7903146(C/t) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians. Metabolism Clinical and Experimental.  2007;56:1174-1178.
6.
Radha V, Mohan V. Genetic prediposition to type 2 diabetes among Asian Indians. Indian Journal of Medical Research. 2007;125:259-274.
7.
Vimaleswaran KS, Radha V, Deepa R, Mohan V. Absence of association of metabolic syndrome with PPARGC1A, PPARG and UCP 1 gene polymorphisms in Asian Indians. (CURES-30). Metabolic syndrome and Related Disorders. 2007;5(2):153-162.
8.
Radha V, Vimaleswaran KS, Ayyappa KA, Mohan V. Association of lipoprotein lipase gene polymorphisms with obesity and type 2 diabetes in an Asian Indian population. (CURES-28). International Journal of Obesity. 2007;31:913-918.
9.
Radha V, Vimaleswaran KS, Babu S, Deepa R, Anjana M, Ghosh S, Majumder PP, Rao MRS,  Mohan V. Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians (CURES-27). Diabetic Medicine.  2007;24(4):398-402.
10.
Bodhini D, Radha V, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. The G1057Dpolymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians. Int J Obes 31: 97-102, 2007. 
11.
Radha V, Vimaleswaran KS, Babu HNS, Abate N, Chandalia M, Satija P,  Grundy SM,  Ghosh S, Majumder PP, Deepa R, Rao SMR, Mohan V.  Role of genetic polymorphism peroxisome proliferator – Activated Receptor – 2 Pro 12Ala on ethnic susceptibility to diabetes in south Asian and Caucasian subjects.  Diabetes Care.  29: 1046-1051, 2006.
12.
Radha V, Mohan V. Genetics of Type 2 diabetes in Asian Indians. In: Type 2 Diabetes in South Asians : Epidemiology, Risk Factors and Prevention. Mohan V, Gundu HR Rao (Eds), Under the Aegis of SASAT. Jaypee Brothers Medical Publishers. 2006, pp.173-185.
13.
Vimaleswaran KS, Radha V, Anjana M, Deepa R, Ghosh S, Majumder PP, Rao MRS, Mohan V. Thr394Thr polymorphism of PPARGC1A gene is associated with Type 2  diabetes and total body fat in Asian Indians.  International Journal of Obesity (Letter to the Editor).  2006; doi:10.1038/sj.ijo.0803484.
14.
Vimaleswaran KS, Radha V, Mohan V. Thr54 allele carriers of the Ala54 Thr    variant of FABP2 gene have associations  with metabolic syndrome and  hypertriglyceridemia in urban south Indians. Metabolism Clinical and Experimental.  55; 2006: 1222-1226.
15.
Vimaleswaran KS, Radha V, Anjana M, Deepa R, Ghosh S, Majumder PP, Rao MRS, Mohan V.  Effect of polymorphisms in the PPARGC1A gene on body fat in Asian IndiansInternational Journal of Obesity. 30:884-91,2006.
16.
Ramprasad S, Radha V, Mathias RA,Majumder PP, Rao MR, Rema M. Rage gene promoter polymorphisms and diabetic retinopathy in a clinic-based population from South India. Eye (UK). 2006, doi:10.1038/sj.eye.6702239.
17.
Radha V, Mohan V, Ashok AK, Deepa R, Mathias RA.  Association of Lipoprotein Lipase Hind III and Ser 447 Ter Polymorphisms with dyslipidemia in Asian Indians.  American Journal of Cardiology.  97: 1337-1342,2006.
18.
Anuradha S, Radha V, Deepa R, Hansen T, Carstensen B, Pederson O, Mohan V.  A prevalent amino acid polymorphism at Codon 98 (Ala98Val) of the Hepatocyte Nuclear Factor-1a is associated with maturity onset diabetes of the young and younger age at onset of Type 2 diabetes in Asian Indians.  Diabetes Care. 28; 2430-2435, 2005.
19.
Guettier JM, Georgopoulos A, Tsai MY, Radha V, Shanthirani S, Deepa R, Gross M, Gundu Rao, Mohan V.  Polymorphisms in the fatty acid-binding protein 2 and apolipoprotein C-III genes are associated with the metabolic syndrome and dyslipidemia in a south Indian populationJournal of Clinical Endocrinology and Metabolism.  90: 1705-1711, 2005.
20.
Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Deepa R, Babu HNS, Rao MRS, Mohan V. Peroxisome proliferators-activated receptor- co-activator -1 (PGC-1) gene polymorphisms and their relationship to Type 2 diabetes in Asian Indians. Diabetic Medicine.  22: 1516-1521,2005.
21.
Nicola Abate, Chandalia M,  Satija P, Adams-Huet B, Grundy SM, Sandeep S, Radha V, Deepa R, Mohan V.  ENPP1/PC-1  K1 21Q Polymorphism and genetic susceptibility to Type 2 diabetes.  Diabetes. 54; 1207-1213, 2005.
22.
Mohan V, Deepa R, Pradeepa R, Vimaleswaran KS, Anjana Mohan, Velmurugan K,    Radha V. Assoiation of low adiponectin levels with the metabolic syndrome – the   Chennai Urban Rural Epidemiology Study (CURES-4). Metabolism Clinical and Experimental. 54; 476-481, 2005.
23. Mohan V, Balasubramanyam M, Radha V. Genomics and Proteomics of Type 2 Diabetes in Indians. (Editorial). Journal of the Association of Physicians of India. 53:507-509, 2005.
24. Kumar D, Sanjeevi CB, Radha V,  Mohan V. Diabetes Mellitus and related disorders.  In : Genetic disorders of the Indian Subcontinent. Dhavendra Kumar(ed).  Klumar Academic Publishers, The NetherLands.413-445, 2004.
25. Radha V, Vimaleswaran KS, Deepa R, Mohan V.  The Genetics of Diabetes Mellitus.  Indian Journal of Medical Research.117:225-238, 2003.
26. Radha V, Rema M, Mohan V. Genes and Diabetic retinopathy. Indian Journal of Ophthalmology.50: 5-11, 2002.
   
  #
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